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Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-On Treatment

£148.00
+Derma Points

Advanced daily exosome treatment that helps regenerate, smooth and firm skin while boosting radiance and supporting long-term skin renewal.

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Order by 3PM weekdays for same day dispatch
Dry Skin
Sensitive Skin
Redness & Rosacea
Wrinkles
Pigmentation
Combination Skin Combination Skin

Dermalogica Phyto Nature E² Regenerating Daily Exosome Leave-On Treatment is a next-generation daily leave-on treatment designed to visibly regenerate, smooth and revitalise the skin using advanced exosome technology and high-performance phytoactives. This innovative formula supports skin renewal across multiple layers of the skin’s surface, helping to reduce the appearance of fine lines, uneven tone and dullness while promoting a firmer, more luminous-looking complexion.

Powered by a regenerative blend of plant-derived, vegan exosomes, this advanced treatment helps support skin regeneration and visibly smooth the signs of ageing. Gentle enzymatic exfoliation works daily to refine texture and reveal brighter skin, while a botanical renewal complex encourages natural exfoliation and improved skin smoothness for a refined, radiant appearance.

Hydration-boosting and antioxidant-rich actives help strengthen the skin barrier and protect against environmental stressors, leaving skin feeling smoother, firmer and more resilient. Ideal for those seeking visible rejuvenation and long-term skin vitality, this lightweight leave-on treatment helps restore radiance and support healthier-looking, youthful skin.

Benefits

  • Supports visible skin regeneration and renewal
  • Helps reduce the appearance of fine lines and wrinkles
  • Refines texture and promotes a brighter, smoother complexion
  • Strengthens the skin barrier and enhances resilience
  • Boosts hydration while defending against environmental stressors

Key Ingredients

  • Regenerative Exosome Blend – plant-derived vegan exosomes help support regeneration across multiple layers of skin’s surface and visibly reduce fine lines and wrinkles
  • Pumpkin Enzyme – gently exfoliates by breaking down dead skin cell bonds to reveal brighter, smoother-looking skin
  • Botanical Renewal Complex (Phyto Glycogen & Prickly Pear) – helps boost skin’s natural exfoliation, smoothness and radiance
  • Bio-Fermented Acetyl Glucosamine – hydrates while providing antioxidant protection and supporting skin resilience
  1. Cleanse
    Start with PreCleanse to remove makeup, SPF and daily buildup. Follow with Special Cleansing Gel to gently cleanse without stripping skin.
    Optional: Use Daily Microfoliant after cleansing if part of your routine.
  2. Renew with Phyto Nature E²
    Apply Phyto Nature E² to clean skin as your first leave-on step. Allow it to absorb fully - for best results use morning and night.
  3. Layer serums and moisturisers
    Once absorbed, layer your usual serums and moisturiser. Phyto Nature E² works seamlessly with other treatments.
    Pro Tip:Follow with Phyto Nature Firming Serum and Phyto Nature Oxygen Cream for enhanced results.
  4. Protect (daytime only)
    Finish with a broad-spectrum SPF, such as Dynamic Skin Recovery SPF50. Apply generously as the final step in your routine.

100ml

Water/Aqua/Eau, Simmondsia Chinensis (Jojoba) Seed Oil, Glycerin, Neopentyl Glycol Diheptanoate, Squalane, Hydrogenated Ethylhexyl Olivate, Propanediol, Caprylic/Capric Triglyceride, Pentylene Glycol, Camellia Japonica Seed Oil, Butylene Glycol, C12-15 Alkyl Benzoate, Sodium Hyaluronate, Ubiquinone, Glycine Soja (Soybean) Oil, PEG-40 Hydrogenated Castor Oil, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Viola Odorata Leaf Extract, Carthamus Tinctorius (Safflower) Seed Oil, Tropaeolum Majus Flower/Leaf/Stem Extract, Astragalus Membranaceus Root Extract, Spilanthes Acmella Flower/Leaf/Stem Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Ligustrum Lucidum Seed Extract, Citrus Aurantium Dulcis (Orange) Oil, Rosmarinus Officinalis (Rosemary) Flower/Leaf/Stem Extract, Salvia Sclarea (Clary) Extract, Litsea Cubeba Fruit Oil, Mentha Piperita (Peppermint) Flower/Leaf/Stem Extract, Luffa Cylindrica Root Extract, Hydrogenated Olive Oil Unsaponifiables, Tocopherol, Phospholipids, Glycogen, Caprylyl Glycol, Glycolipids, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glycine Soja (Soybean) Sterols, Dicaprylyl Ether, Xanthan Gum, C15-19 Alkane, Ethylhexylglycerin, Polysorbate 20, Tetrasodium Glutamate Diacetate, Phytic Acid, Lauryl Glucoside, Sodium Hydroxide, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Benzoate.

Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.

Dermalogica is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are complete, up-to-date and/or error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.

Dermalogica

Since its launch in 1986, Dermalogica has transformed the professional skincare industry with its commitment to education, innovation and skin health. Developed by skin therapists for skin therapists, the brand focuses on real results rather than luxury packaging or gimmicks.


Every product is formulated without common irritants such as artificial fragrance or colours, making it suitable for even sensitive skin. Dermalogica’s broad portfolio spans cleansers, exfoliants, targeted treatments and SPF, built around customisable professional treatments and homecare routines.


With its iconic grey packaging and clinical approach, Dermalogica continues to lead the way in evidence-based skincare, supporting professionals with cutting-edge education and empowering consumers to achieve their healthiest skin ever.

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Ingredient
Peptides
Antioxidants
Vitamin C
What It Is

Vitamin C is an essential nutrient required for the growth and repair of tissues in all parts of the body, including the skin, but we cannot produce it on our own. The powerful antioxidant is found naturally in fruits and vegetables and commonly produced synthetically in skincare products, such as moisturisers, toners, and, most often, serums.

What It Does

How to use in your skincare routine?

Whether your skin is dry, oily, or a combination, vitamin C is beneficial for skin health, helping it look and feel healthier and younger longer.

Before you apply the vitamin C, test a patch of skin with a lower-concentration formula to see how your skin reacts. Some minor tingling is normal, but if you experience anything more intense, stop using the product and talk to your dermatologist.

For best results, apply this vitamin topically 1-2 times a day, morning and night. Be sure to apply a moisturiser with a broad-spectrum SPF after vitamin C application for daytime.

Benefits
  • Vitamin C makes sun damage and surface pigment spots less visible and brightens a dull, blotchy skin.
  • It is a powerful antioxidant that protects the skin from irritation, inflammation and environmental pollution.
  • It reduces red blotches left after spots by improving the skin’s natural healing process.
  • It increases the effectiveness of sunscreen and gives the skin better protection from UV rays