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Endocare Renewal Retinoid Serum
Endocare Renewal Retinoid Serum
Endocare Renewal Retinoid Serum
Endocare Renewal Retinoid Serum
Endocare Renewal Retinoid Serum
Endocare Renewal Retinoid Serum
Endocare Renewal Retinoid Serum
Endocare Renewal Retinoid Serum

Endocare Renewal Retinoid Serum

£55.00
+Derma Points

A dual-retinoid night serum with RETINDUO® technology to smooth fine lines and refine texture, with niacinamide and hyaluronic acid for comfort.

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Helps with

Fine lines and wrinkles

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Endocare Renewal Retinoid Serum is a dual-retinoid serum designed to visibly smooth fine lines, refine texture and support firmer-looking skin. Exclusive RETINDUO® technology combines pure retinol in microsponges with AOX-TECH® encapsulated retinal, supported by a natural booster complex.

Its intelligent dual-delivery system optimises retinoid performance while helping to minimise irritation. Cross-linked hyaluronic acid and niacinamide support hydration and reinforce the skin barrier.

After 28 days, 90% of users reported softer skin and reduced fine lines, and 85% noticed improved texture. Fragrance-free and suitable for all skin types, it is the first step in the Endocare Renewal Retinoid progression.

Benefits

  • Visibly smooths fine lines and wrinkles.
  • Refines skin texture.
  • Supports firmer-looking skin.
  • Designed for enhanced tolerance.
  • Fragrance-free in airless, airtight packaging.
  • The ideal starting point before the Intensive Serum.

Key Ingredients

  • RETINDUO® Technology: Pure retinol in microsponges with AOX-TECH® encapsulated retinal for controlled renewal.
  • 3% Cross-Linked Hyaluronic Acid: Long-lasting hydration and visible plumping.
  • 4% Niacinamide: Supports the barrier, improves tone and enhances retinoid tolerance.
  • Apply a pea-sized amount to cleansed face and neck at night.
  • Begin twice weekly and increase frequency gradually as tolerated.
  • Use a broad-spectrum SPF such as Heliocare daily.
  • Avoid the eyes, eye contour and mucous membranes. Mild peeling at first is normal.
  • Not recommended during pregnancy or breastfeeding. Contains vitamin A.

30ml

Aqua; Propanediol; Niacinamide; Sodium Carboxymethyl Starch; Undecane; Caprylic/Capric Triglyceride; Polyglyceryl-6 Distearate; Glycerin; Tridecane; Pentylene Glycol; Retinol; Retinal; Phytol; Chamomilla recutita Flower Extract; Phosphatidylcholine; Mannitol; Tocopheryl Acetate; Tocopherol; Jojoba Esters; Cellulose; Polyacrylate Crosspolymer-6; Dimethyl Isosorbide; Polyglyceryl-3 Beeswax; Cetyl Alcohol; Trisodium Ethylenediamine Disuccinate; Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate; Hexamidine Diisethionate; Diutan Gum; Polyglyceryl-10 Laurate; Sodium Hyaluronate Crosspolymer; Hesperidin; Ethylhexylglycerin; Sodium Sulfite; Citric Acid; BHT.

Endocare

Endocare is a dermatologist-developed brand built on more than two decades of research into skin regeneration. At its heart is SCA® Biorepair Technology, a patented growth factor complex derived from snail secretion that stimulates fibroblast activity, collagen synthesis and tissue repair.


The Endocare range includes serums, creams and ampoules targeting photoageing, loss of firmness, and post-procedure recovery. Clinical studies show significant improvements in skin texture, elasticity and fine lines.


Recommended by dermatologists worldwide, Endocare combines biotech innovation with high tolerability, making it an ideal choice for ageing or compromised skin seeking visible renewal.

Vitamin A / Retinol, Niacinamide, Hyaluronic Acid, Vitamin E, Glycerin
Vitamin A explained: retinol, retinal and why you should start low

Further reading from The Derma Edit

Vitamin A explained: retinol, retinal and why you should start low

Read the guide

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Ingredient
Vitamin A / Retinol
What It Is

Vitamin A / Retinol plays a bunch of key roles in the body, and it’s essential when it comes to the health of your skin. It’s involved in the production of fresh, new cells, which keeps your skin both functioning and looking its best.

Vitamin A contains retinoids, compounds that come in many forms such as:

  • Retinol - Once in the middle layer of skin, retinol helps neutralise free radicals. This helps boost the production of elastin and collagen, which creates a “plumping” effect that can reduce the appearance of, fine lines, wrinkles and enlarged pores
  • Retinyl -This is the least irritating of all four retinoids, it's a great option for almost all skin types and anyone who wants to keep their pores clear and skin youthful. It promotes skin cell turnover, improves skin tone, helps unclog pores and helps thicken the dermis to slow down the formation of wrinkles.
  • Retinal - This is the only retinoid that exhibits direct antibacterial properties. This makes it perfect for those prone to blemishes. With continued use, it diminishes the bacteria responsible for breakouts to leave skin looking clear, radiant and youthful.
What It Does

How to use in your skincare routine?

We recommend them as part of a nightly skin care routine, when most people don’t mind adding an extra step or two. But it’s also fine to use Vitamin A / Retinol in the daytime, as long as you finish with a broad-spectrum sunscreen rated SPF 30 or greater.

Don’t forget—when you apply your Vitamin A / Retinol product, be sure to include your neck and chest so you get those amazing benefits there, too.

Benefits

Retinoids can help exfoliate skin on the surface, removing dirt, oil, and dead skin cells from pores to prevent pimples. They also penetrate the skin’s surface to stimulate collagen and elastin production, which can help reduce the appearance of pores and acne scarring.

Vitamin A / Retinol , works to reduce the appearance of fine lines and wrinkles by stimulating collagen production.

Niacinamide
What It Is

Although the word Niacinamide may sound a little scary, it’s basically Vitamin B3, an essential nutrient for your skin. This is why Niacinamide can help your skin look healthier.

It can be found in vitamin-rich foods, such as kale, mushrooms and almonds, which help take great care of your body from the inside, as well as in our skin care products to pamper it from the outside.

What It Does

Niacinamide is a true multitasker. From boosting hydration to protecting the skin from environmental damage, it offers a wide variety of benefits. It penetrates your skin and helps renew your complexion from within.

Benefits

Although Niacinamide may be less talked about than the wonder ingredient of the decade, retinol, its benefits are just as significant. Here are some of the most amazing skin benefits of Niacinamide:

  • Increases the skin’s ability to maintain hydration. Niacinamide strengthens your skin’s moisture barrier to improve its ability to hold on to moisture. Your skin is less likely to dry out and will stay hydrated for longer. If dry skin is a concern for you, view the range here.
  • Improves skin texture. It helps reduce the size of your pores while keeping your skin moisturised.
  • Rejuvenates the eye area. The skin around your eye is extremely delicate, and this is where usually the first signs of skin ageing appear. Niacinamide can help with these skin concerns and reduce the appearance of fine lines and wrinkles for younger-looking eyes.
  • Helps with dark spots and hyperpigmentation. Niacinamide’s is a true multitasker, it can also help lighten dark spots and the marks of hyperpigmentation.
  • Aids surface skin cell regeneration for younger-looking skin. By locking in moisture, Niacinamide provides your skin with the moisture it needs for natural skin cell turnover to take place properly.
  • Helps with oily skin. Niacinamide helps regulate sebum production and this can help control oily skin.
Hyaluronic Acid
What It Is

Hyaluronic-acid a substance that retains moisture and is capable of binding over one thousand times its weight in water. This substance is naturally found in many areas of the human body, including the skin, eyes, and synovial fluid of the joints.

As we age, the production of key substances in the skin, including hyaluronic acid (along with collagen and elastin) decreases. As a result, our skin loses volume, hydration, and plumpness.

The substance works as a magnet for moisture, helping your cells retain as much of it as possible so that your skin feels and appears hydrated, plump and healthy.

What It Does

Moisturisers and serums are two of the most common form of hyaluronic acid.

  • Moisturisers. Use a moisturiser infused with hyaluronic acid at the time when you’d usually moisturise. Ideally, this would be 2 times a day and always after cleansing, exfoliating, or applying serums.
  • Serums. A hyaluronic acid serum involves a slightly different routine. After cleansing, use a toner on your skin and press a couple of drops of your serum into your face with the palms of your hands. Don’t forget to apply a moisturiser immediately afterward to seal in all that hydration.

This acid also plays well with most other skin actives, making it easy to pair with peels, retinols, vitamins, and other acids.

Benefits

When used in skincare products, including creams and serums, hyaluronic acid gives your complexion a boost by quickly increasing the skin's moisture level. It’s especially useful for reducing the appearance of wrinkles and age lines.

Vitamin E
What It Is

Vitamin E is a fat-soluble, essential nutrient with anti-inflammatory properties. Vitamin E helps support the immune system, cell function, and skin health. It’s an antioxidant, making it effective at combating the effects of free radicals produced by the metabolism of food and toxins in the environment.

Vitamin E is a powerful antioxidant that may be effective at reducing UV damage in skin. And when applied topically may help nourish and protect your skin from damage caused by free radicals.

What It Does

How to use in your skincare routine?

It can be used underneath moisturiser and sunscreen in the morning [if it’s a vitamin E oil] and is sometimes combined with other antioxidants, such as Vitamin C in Serums.

Best suited for those with dry, very dry, or mature skin.

Avoid using if you have very oily, acne prone skin or those prone to sensitivity.

Benefits

In moisturisers it can:

  • Stop skin from losing moisture.
  • Protect cells from damage.
  • Soften skin.
Glycerin
What It Is

Glycerin works as a humectant, it attracts moisture from the air into the stratum corneum (top layer of skin), and due to its low molecular weight, will continue to draw moisture to the deeper layers of the dermis.

Glycerin also treats several skin disorders, ranging from dry skin to wound healing. The ingredient has the potential of improving your overall internal health as well.

Due to its versatility and ability to moisturise, it’s used in everything from lotions to soaps to toners.

What It Does

How to use in your skincare routine?

Products with glycerin can be used topically multiple times a day. You can safely and effectively use this ingredient in nearly every single step of your skin care routine. Several skin care brands use glycerin when formulating everything from cleansers and toners, to serums and moisturisers.

Benefits
  • Glycerin tightens and firms - Use this ingredient for a few weeks or even a few days and we think you'll find that it plumps and softens your look significantly, especially if you have more mature skin.
  • It improves your complexion - Glycerin is non-comedogenic, meaning it won’t clog pores.
  • It brightens - Between glycerin’s rejuvenating properties and its ability to moisturise, glycerin plays a key role in keeping skin looking bright and luminous.
  • The ingredient is also a good choice for sensitive skin. Because it’s a natural component of skin, it calms redness and inflammation. It’s one of the gentler ingredients you can find in skin care products and can even help alleviate sensitivity over time.